He regularly appears in such concert halls as Teatro alla Scala in Milan, Salle Gaveau and Salle Pleyel in Paris, Lincoln Center in New York, the Concertgebouw in Amsterdam, the Philharmonic Society of Brussels, the Great Hall of Moscow Conservatory,  the Hamburger Musikhalle, the Berlin Konzerthaus and the Tivoli of Copenhagen.  He worked with  notable conductors like R. Chailly, G. Noseda, A. Ceccato, P. Eötvös, V. Jurowski, S. Denéve, G. Neuhold and  with orchestras such as the Staatskapelle Dresden, Indianapolis Symphony Orchestra, Netherlands Chamber Orchestra, Royal Liverpool Philharmonic, Hong Kong Philharmonic, Orchestre de Concerts Lamoureux, Rotterdam Philharmonic, Orquesta RTVE of Madrid, BBC Scottish, Netherlands Philharmonic, Orchestra Sinfonica di Milano 'G.Verdi', Radio Chamber Orchestra Holland, and many others.

Dedicatee of various contemporary works  composed by A. Corghi, L. Francesconi, F. Vacchi, C. Galante and U. Leyendecker, he recorded for Deutsche Grammophon, Amadeus, Nuova Era, Dynamic, Warehouse, etc.

Marco Rizzi teaches since 1999  at the Hochschule für Musik -Detmold, in October 2008 he has been appointed at the Hochschule für Musik in Mannheim and is also professor at the renomated Escuela Superior de Musica Reina Sofia in Madrid. He is also regularly serving as juror in some of the most prestigious violin competitions, such as the Queen Elisabeth Competition (Bruxelles), the Joachim Violin Competition (Hannover) or the Paganini Violin Competition (Genova).

Marco Rizzi plays on the “Baron Knoop” 1743 violin by Pietro Guarneri, owned by the foundation “Il Canale” ONLUS.